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glossary:promoter

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glossary:promoter [2024/09/01 15:54] – created mikeglossary:promoter [2024/09/01 15:58] (current) mike
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   * In bacteria, a promoter is a cis-acting DNA sequence near the transcription start site of a gene or operon that binds to bacterial RNA polymerase.    * In bacteria, a promoter is a cis-acting DNA sequence near the transcription start site of a gene or operon that binds to bacterial RNA polymerase. 
 +  * In eukaryotes, the formal definition of a promoter (also called a basal promoter) is a cis-acting DNA sequence near the transcription start site of a gene that binds to the basal transcription factors (also called general transcription factors), which collectively form a scaffold upon which eukaryotic RNA polymerase (usually RNA pol II) can bind to form the transcription initiation complex. The TATA box is a component within the promoter of most eukaryotic genes.
 +  * In a general and less formal sense, "promoter" refers to any DNA sequences near a gene that regulates its expression. In this informal usage, "promoter" can be refer to a region of DNA thousands of bp in size and can include enhancer sequences.   
glossary/promoter.1725231293.txt.gz · Last modified: 2024/09/01 15:54 by mike