In
eukaryotesplugin-autotooltip__default plugin-autotooltip_bigeukaryote: organism whose cells have membrane bound organelles, including the nucleus., the formal definition of a promoter (also called a basal promoter) is a
cisplugin-autotooltip__default plugin-autotooltip_bigCis and trans: In genetics, cis and trans are terms used to describe the relative physical locations of genes or genetic elements. If two genes are in cis, this means that they are physically located on the same DNA molecule. If two genes are in trans, this means that they are physically located on two different-acting
DNAplugin-autotooltip__default plugin-autotooltip_bigDNA: deoxyribonucleic acid. The genetic material for nearly all life on Earth. sequenceplugin-autotooltip__default plugin-autotooltip_bigSequence: the precise order of monomers in a polymer. In DNA, it refers to the order of G, A, T, and C nucleotides. In RNA, it refers to the order of G, A, U, and C nucleotides. In proteins, it refers to the order of amino acids. near the
transcriptionplugin-autotooltip__default plugin-autotooltip_bigRNA transcription: the process of RNA polymerase using the DNA sequence of a gene as a template to form an mRNA (in prokaryotes) or pre-mRNA (in eukaryotes). In most cases, “transcription” implies RNA transcription. start site of a
geneplugin-autotooltip__default plugin-autotooltip_bigGene: read Chapters 02, 03, 04, 05, and 06 for a definition of gene :-) that binds to the basal
transcription factorsplugin-autotooltip__default plugin-autotooltip_bigTranscription factor: a generic term that describes any DNA binding protein that affects transcription (can havea positive or negative effect on transcription). (also called general
transcription factorsplugin-autotooltip__default plugin-autotooltip_bigTranscription factor: a generic term that describes any DNA binding protein that affects transcription (can havea positive or negative effect on transcription).), which collectively form a scaffold upon which
eukaryoticplugin-autotooltip__default plugin-autotooltip_bigeukaryote: organism whose cells have membrane bound organelles, including the nucleus. RNA polymeraseplugin-autotooltip__default plugin-autotooltip_bigRNA polymerase: the enzyme that carries out RNA transcription. There are many different types of RNA polymerase, but in this book we collectively refer to them as just “RNA polymerase” for simplicity. (usually RNA pol II) can bind to form the
transcriptionplugin-autotooltip__default plugin-autotooltip_bigRNA transcription: the process of RNA polymerase using the DNA sequence of a gene as a template to form an mRNA (in prokaryotes) or pre-mRNA (in eukaryotes). In most cases, “transcription” implies RNA transcription. initiation complex. The
TATA boxplugin-autotooltip__default plugin-autotooltip_bigTATA box: a short DNA sequence (usually just 6 bp long) that is part of most eukaryotic promoters located around 35-40 bp upstream of the transcription start site. It is the binding site for TATA binding protein (TBP). is a component within the promoter of most
eukaryoticplugin-autotooltip__default plugin-autotooltip_bigeukaryote: organism whose cells have membrane bound organelles, including the nucleus. genesplugin-autotooltip__default plugin-autotooltip_bigGene: read Chapters 02, 03, 04, 05, and 06 for a definition of gene :-).