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glossary:crispr [2024/09/01 21:25] mikeglossary:crispr [2024/09/01 21:26] (current) mike
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-CRISPR: short for clustered regularly interspaced short palindromic repeats. In bacteria, CRISPR is a form of innate immunity that bacterial cells use as a defense against bacteriophage. The CRISPR system consists of a protein typically called Cas9 and two non-coding RNAs called gRNA and tracrRNA. The gRNA directs the CRISPR/Cas9 enzyme to a DNA target based on base pairing between the gRNA sequence and the target DNA.+%%CRISPR%%: short for clustered regularly interspaced short palindromic repeats. In bacteria, %%CRISPR%% is a form of innate immunity that bacterial cells use as a defense against bacteriophage. The %%CRISPR%% system consists of a protein typically called %%Cas9%% and two non-coding RNAs called %%gRNA%% and tracrRNA. The %%gRNA%% directs the %%CRISPR/Cas9%% enzyme to a DNA target based on base pairing between the %%gRNA%% sequence and the target DNA.
  
-Scientists have co-opted the CRISPR/Cas9 system as a research tool that can be used to cleave dsDNA at nearly any desired location with a high degree of specificity. They do this by modifying the gRNA sequence to match a desired target DNA. +Scientists have co-opted the %%CRISPR/Cas9%% system as a research tool that can be used to cleave dsDNA at nearly any desired location with a high degree of specificity. They do this by modifying the %%gRNA%% sequence to match a desired target DNA. 
glossary/crispr.1725251105.txt.gz · Last modified: 2024/09/01 21:25 by mike