glossary:crispr
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- | CRISPR: short for clustered regularly interspaced short palindromic repeats. In bacteria, CRISPR is a form of innate immunity that bacterial cells use as a defense against bacteriophage. The CRISPR system consists of a protein typically called Cas9 and two non-coding RNAs called gRNA and tracrRNA. The gRNA directs the CRISPR/Cas9 enzyme to a DNA target based on base pairing between the gRNA sequence and the target DNA. | + | %%CRISPR%%: short for clustered regularly interspaced short palindromic repeats. In bacteria, |
- | Scientists have co-opted the CRISPR/Cas9 system as a research tool that can be used to cleave dsDNA at nearly any desired location with a high degree of specificity. They do this by modifying the gRNA sequence to match a desired target DNA. | + | Scientists have co-opted the %%CRISPR/Cas9%% system as a research tool that can be used to cleave dsDNA at nearly any desired location with a high degree of specificity. They do this by modifying the %%gRNA%% sequence to match a desired target DNA. |
glossary/crispr.1725251105.txt.gz · Last modified: 2024/09/01 21:25 by mike